منابع مشابه
Characterization of brainstem peptide YY (PYY) neurons.
Peptide YY (PYY), a member of the NPY superfamily of peptides, is predominantly synthesized by the colon and is thought to act on both the gut and brain to modulate energy homeostasis. Although neurons expressing PYY mRNA have also been reported in the brainstem, little is known about their physiological role and study of their projections has been problematic due to crossreactivity of PYY anti...
متن کاملGhrelin and peptide YY (PYY) profiles in gastrointestinal tissues and the circulation of the rat during pregnancy and lactation.
Plasma and tissue profiles of gastrointestinal hormones ghrelin and peptide YY (PYY) were investigated in different female rat reproductive states. Neither plasma nor tissue ghrelin concentrations were suppressed during pregnancy despite elevated leptin. The highest concentrations of stomach ghrelin were measured in late pregnancy. PYY concentrations in plasma, descending colon and rectum tissu...
متن کاملThe Association of Serum Total Peptide YY (PYY) with Obesity and Body Fat Measures in the CODING Study
BACKGROUND PYY is an appetite suppressing hormone. Low circulating PYY has been linked to greater BMI. However data is controversial and this association has not been verified in large human populations. OBJECTIVE The purpose of this study was to investigate if fasting serum total PYY is associated with obesity status and/or adiposity at the population level. DESIGN A total of 2094 subjects...
متن کاملPeptide YY: obesity's cause and cure?
RECENTLY, the United States Food and Drug Administration (FDA) decided for the present against approving the cannabinoid receptor antagonist Rimonabant for the treatment of obesity in the United States. This decision resulted mainly from concerns based on studies showing that the drug’s benefits would not outweigh its risks for side effects. This decision further diminished already limited hope...
متن کاملPeptide YY: a neuroendocrine neighbor of note.
Endocrine cells, enteric neurons and enterocytes provide an integrated functional defense against luminal factors, including nutrients, microbes and toxins. Prominent among intrinsic mediators is peptide YY (PYY) which is present in approximately 50% of colorectal endocrine cells and neuropeptide Y (NPY), a neurotransmitter expressed in submucous and myenteric nerves. Both peptides and their lo...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2012
ISSN: 1768-3262
DOI: 10.4267/2042/46002